Diagnostic Test Directory

Virology Laboratory

Measles (Rubeola) IgG serology - serum specimen

  • LIS Mnemonic: SMIM

    Collect

    Gold (SST - Clot activator & gel)

    Volume Required

    2 ml blood

    Minimum Required

    1 ml serum

    Transport

    Room temperature

    Stability

    N/A

    Processing

    If multiple viral serologies are being requested from the same specimen, the general rule is to collect a total of 2-4 ml of blood for every 2-3 tests ordered. A single serum specimen is required to determine the immune status of an individual or to test for viral-specific IgM antibodies. Paired sera specimens, collected two to three weeks apart, are required for the diagnosis of a current or recent viral infection when examining specimens for IgG antibody. Obtain the acute phase serum as soon as possible after the onset of illness. The most useful results are obtained by submitting acute and convalescent phase sera together to be tested simultaneously. Serological testing is not usually available for body fluids other than serum. However, in patients with viral neurologic disease (e.g., measles acute encephalitis or measles subacute sclerosing panencephalitis (SSPE)), cerebrospinal fluid (CSF) may be tested for measles antibody if paired with a serum specimen from the same date.

Days Performed

Thursday

Reported

Same day

Reflex Testing

N/A

CPT

86765

Methodology

Enzyme Immunoassay

Interpretation

<0.9 - No measles (rubeola) IgG antibody detected 0.9-1.10 - Equivocal for measles (rubeola) IgG antibody >1.10 - Positive for measles (rubeola) IgG

Reference Values

Negative or no measles (rubeola) IgG antibody detected

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